Risk and Central Monitoring Associate Manager (UK/Europe)

About the role

Worldwide Clinical Trials, a global CRO, is hiring a Risk and Central Monitoring Associate Manager for a remote role open to candidates based in the UK and Europe. The role supports risk management and central monitoring across global clinical trials, helping study teams identify, assess and mitigate risks so that trials follow ICH GCP guidelines and deliver consistent quality and patient outcomes.

Key responsibilities

• Lead and oversee Risk-Based Quality Management (RBQM) activities for assigned clinical trials, aligned with study objectives and regulatory expectations.
• Develop and maintain Central Monitoring Plans, secure the required approvals and support study oversight.
• Coordinate cross-functional risk assessments and help identify key study risks, KRIs and QTLs where applicable.
• Train and guide study teams on RBQM, central monitoring and risk management.
• Perform central monitoring reviews, analysing trends, outliers and risk signals and recommending actions.
• Maintain high-quality risk management and central monitoring documentation to support inspection readiness.
• Support technology activities such as user acceptance testing of RBQM tools and central monitoring solutions.
• Take part in sponsor meetings, bid defences, audits and other stakeholder engagements as required.

Required profile

• BSc, Registered Nurse qualification or an equivalent combination of education, skills and experience.
• At least 4 years of clinical research experience, including a minimum of 3 years in Risk-Based Monitoring and relevant ICH/regulatory guidance.
• Previous experience as a Central Monitor or within a central monitoring function.
• Ability to work across functions and in global, cross-cultural teams.
• Proficiency in English.

Required skills

• Strong understanding of RBQM principles, risk assessment methods, KRIs, QTLs and study monitoring strategies.
• Ability to analyse complex data, spot trends and outliers and turn findings into risk insights.
• Critical thinking, problem solving, communication, presentation, organisation and Microsoft Office skills.